Cancer Research Journal

Volume 3, Issue 2, March 2015

  • Association of Superoxide Dismutase, Glutathione Peroxidase, Catalse, and Xanthine Oxidase with Incidence of Bladder Cancer

    Shatha Rouf Moustafa

    Issue: Volume 3, Issue 2, March 2015
    Pages: 17-27
    Received: Mar. 06, 2015
    Accepted: Mar. 19, 2015
    Published: Mar. 23, 2015
    Abstract: Background: Emerging evidence indicates a potential role of anti-oxidant enzymes in the prevention of bladder cancer. Aims: This study assessed the correlation between the anti-oxidative enzymes with bladder cancer incidence. The present study was aimed to estimate the levels of superoxide dismutase, glutathione peroxidase, catalase and xanthine ox... Show More
  • Clinical Utility of Altered Expressions of P53,Vascular Endothelial Growth Factor and Survivin in Patients with Bladder Cancer

    Ahmed Nabeel Ahmed, Shatha Rouf Moustafa

    Issue: Volume 3, Issue 2, March 2015
    Pages: 28-41
    Received: Mar. 20, 2015
    Accepted: Mar. 28, 2015
    Published: Mar. 31, 2015
    Abstract: Backgroundand Objectives: Bladder cancer is considered a major problem world wide. Aberrant P53, mutant vascular endothelial growth factor and deregulated expression of survivin were used as biochemical markers for investigation, prognosis and follow up. Aims: This study was conducted to assess the prognostic impact of altered expressions of these ... Show More
  • Osteopontin Gene Expression is Inversely Regulate 5-Fluorouracil Drug Resistance in Colon Cancer

    Go Nakajima, Kazuhiko Hayashi, Masakazu Yamamoto

    Issue: Volume 3, Issue 2, March 2015
    Pages: 42-46
    Received: Mar. 28, 2015
    Accepted: Apr. 15, 2015
    Published: Apr. 27, 2015
    Abstract: Background: Resistance to chemotherapeutic drugs complicates the treatment of cancer patients. The extracellular matrix protein osteopontin (OPN) plays multiple roles in the proliferation and metastasis of cancer cells. We therefore attempted to determine whether OPN expression correlated with drug resistance. Methods: OPN expression in the HCT 116... Show More