Cancer Research Journal

Volume 11, Issue 3, September 2023

  • Lentivirus-Mediated Overexpression of miR-218-5p Inhibits Metastasis by Targeting CDH2 in Colorectal Cancer

    Hailong Zhu, Xuyou Zhu, Xiaoli Li, Ran Cui

    Issue: Volume 11, Issue 3, September 2023
    Pages: 86-90
    Received: Mar. 24, 2023
    Accepted: Apr. 12, 2023
    Published: Jul. 06, 2023
    Abstract: Introduction: MicroRNA-218 (miR-218) acts as a tumor suppressor in various types of cancer. However, the association between miR-218-5p, the mature body of miR-218, and colorectal cancer (CRC) metastasis remains unclear. Objective: This study aimed to investigate the effect of miR-218-5p on CRC metastasis in vivo and the underlying molecular mechan... Show More
  • Gastric Cancers: Surgical Management and Prognostic Factors in the General Surgery Department of the National Ignace Deen Hospital, Conakry (Guinea)

    Conde Ansoumane, Fofana Naby, Soumaoro Labile Togba, Kondano Saa Yawo, Fofana Houssein, Toure Aboubacar

    Issue: Volume 11, Issue 3, September 2023
    Pages: 91-93
    Received: May 27, 2023
    Accepted: Jun. 13, 2023
    Published: Jul. 17, 2023
    Abstract: Introduction: gastric cancer remains one of the leading causes of cancer death worldwide. The aim of this work was to study the surgical management and to determine the prognostic factors of gastric cancer in the general surgery department of the Ignace Deen national hospital, Conakry (Guinea). Patients and methods: This was a retrospective descrip... Show More
  • High Accuracy Classification of Populations with Breast Cancer: SVM Approach

    Philip de Melo, Mane Davtyan

    Issue: Volume 11, Issue 3, September 2023
    Pages: 94-104
    Received: Jul. 01, 2023
    Accepted: Jul. 27, 2023
    Published: Aug. 15, 2023
    Abstract: Breast cancer is one of the most common cancers diagnosed in the United States. Breast cancer can occur in both men and women. The number of deaths associated with this disease is steadily declining, largely due to factors such as earlier detection and a new personalized approach to treatment. In this article, we offer a highly accurate and reliabl... Show More
  • Ovarian Cancer After Breast Cancer Treatment: Study of 03 Cases in a Guinean Oncological Setting

    Bah Malick, Toure Alhassane Ismael, Keita Mamady, Cisse Kalil, Souare Mamadou Bobo, Conde Ibrahima Kalil, Cisse Mohamed Falilou, Traore Bangaly

    Issue: Volume 11, Issue 3, September 2023
    Pages: 105-111
    Received: Aug. 16, 2023
    Accepted: Sep. 01, 2023
    Published: Sep. 14, 2023
    Abstract: Introduction: Ovarian cancer, the 1st cause of death from gynecological cancer, is any malignant proliferative process developed in the ovary, which may occur after a treated breast cancer. Objectives: To discuss the management and prognosis of ovarian cancer after breast cancer treatment through a series of 3 clinical cases in a Guinean oncology s... Show More
  • Demographic Profile of Patients with Stage-IV Non-Small Cell Lung Cancer: A Single Center Study in Bangladesh

    Beauty Saha, Muhammad Rafiqul Islam, Nazma Azim, Salman Bashar Al Aub, Rashedul Islam, Ahmed Jabeer

    Issue: Volume 11, Issue 3, September 2023
    Pages: 112-115
    Received: Jul. 22, 2023
    Accepted: Aug. 21, 2023
    Published: Sep. 20, 2023
    Abstract: Background: In Bangladesh, stage IV non-small-cell lung cancer (NSCLC) is the second most common cancer in males among top five most frequent cancers and the increase in lung cancer risk among women reflects changes during the 20th century. Prior conception on the demographic profile of patients with Stage-IV NSCLC may be helpful for the good manag... Show More
  • Breast Cancer in Women Under 40 Years of Age Surgical Oncology Unit of Donka National Hospital a Retrospective Cohort Study

    Malick Bah, Keita Mamady, Touré Alhassane Ismael, Cisse Kalil, Souare Mamadou Bobo, Conde Ibrahima Kalil, Traore Bangaly

    Issue: Volume 11, Issue 3, September 2023
    Pages: 116-121
    Received: Aug. 29, 2023
    Accepted: Sep. 13, 2023
    Published: Sep. 27, 2023
    Abstract: Objective: To describe the epidemiological, clinical, therapeutic and prognostic aspects of breast cancer in women aged 40 years and younger. Material and methods: This was are retrospective descriptive cohort of 128 months, from April 11, 2007, to December 31, 2017; including patients aged 40 years and younger who had been treated and followed up ... Show More