Cancer Research Journal

Volume 7, Issue 1, March 2019

  • Trimodality Bladder Preservation Therapy for Muscle-Invasive Bladder Cancer: Mansoura Experience

    Eman Awad Abd Allah, Fatma Mohamed Farouk Akl, Seham Elsayed-Abd-Alkhalek

    Issue: Volume 7, Issue 1, March 2019
    Pages: 1-7
    Received: 7 December 2018
    Accepted: 19 December 2018
    Published: 24 January 2019
    Abstract: Background & objective: Bladder preservation therapy (BPT) using a trimodality approach represents an alternative option to cystectomy inmuscle-invasive bladder cancer (MIBC) patients, also a treatment option in non-cystectomy candidates. The objective of this study was to evaluate BPT using a trimodality approach composed of maximum TURBT, neoadju... Show More
  • Impact of Neoadjuvant Chemotherapy on Breast Cancer Biomarkers: A Guide for Further Adjuvant Treatment

    Ghada Ezzat Eladawei, Dina Abdallah Elnady, Ashraf Khater, Sheref Mohamed El-taher

    Issue: Volume 7, Issue 1, March 2019
    Pages: 8-17
    Received: 22 January 2019
    Accepted: 27 February 2019
    Published: 20 March 2019
    Abstract: Introduction and objective: There is discrepancy in practice worldwide whether testing molecular profile on residual carcinoma is warranted and if treatment options should be modified according to final molecular profile of tumor. Therefore, the current study was conducted to evaluate potential changes in breast biomarkers; estrogen receptor, proge... Show More
  • Localised Prostate Versus Whole Pelvic Irradiation in High Risk Prostate Cancer, Single Institute Experience

    Rasha Mohamed Abdel Latif, Ghada Ezzat Eladawei

    Issue: Volume 7, Issue 1, March 2019
    Pages: 18-24
    Received: 30 January 2019
    Accepted: 12 March 2019
    Published: 1 April 2019
    Abstract: Objectives: Whole pelvic irradiation [WPRT] versus prostate only radiation [PO-RT] in node negative high risk disease is controversial. This study aims to assess survival benefit of PO-RT against WPRT in high risk negative nodes prostate cancer. Patients and Methods: Patients with high risk prostate cancer and negative pelvic lymph nodes treated ra... Show More
  • Effect of Second Cycle Pre-induction Chemotherapy in Critically Ill Burkitt’s Lymphoma Children

    Emad Moussa, Asmaa Hamoda, Samah Semary, Marwa Romeih, Randa Amin, Omneya Hassanin

    Issue: Volume 7, Issue 1, March 2019
    Pages: 25-32
    Received: 16 February 2019
    Accepted: 25 March 2019
    Published: 18 April 2019
    Abstract: Advanced stage Burkiit’s lymphoma (BL) is associated with tumor burden. Toxicities from intensive therapies are significant. The objectives of this study were to analyze the outcome of patients who could not receive induction chemotherapy on time, and were given a 2nd pre-phase (CVP), and to measure the impact of delay on disease outcome. It is a r... Show More