Cancer Research Journal

Volume 11, Issue 2, June 2023

  • The Mechanism of Ginkgo Biloba Extract in Treating Glioma

    Shihua Liu, Sen Yang, Xiaohui Han, Aixia Sui

    Issue: Volume 11, Issue 2, June 2023
    Pages: 34-43
    Received: Mar. 31, 2023
    Accepted: Apr. 17, 2023
    Published: Apr. 27, 2023
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    Abstract: Objective: To explore the active components of ginkgo biloba and the possible targets and pathways for treating glioma. Methods: The chemical components and corresponding targets of Ginkgo biloba were searched by TCMSP, and the "component-target" network map was constructed by Cytoscape. The GenCards database, OMIM database and Disgenet database we... Show More
  • Research Progress on the Mechanism and Treatment of Ferroptosis in Brain Glioma

    Xiaohui Han, Shihua Liu, Sen Yang, Aixia Sui

    Issue: Volume 11, Issue 2, June 2023
    Pages: 44-48
    Received: Apr. 10, 2023
    Accepted: May 02, 2023
    Published: May 10, 2023
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    Abstract: Ferroptosis is a new type of programmed cell death discovered in recent years. It is a regulatory cell death induced by iron dependent lipid peroxide injury. Ferroptosis plays a critical role in the development of glioma, affecting tumor proliferation, angiogenesis, tumor cell necrosis, and the formation of an immune-resistant tumor microenvironmen... Show More
  • Competitive Risk Analysis of Thymic Carcinoma Based on the Surveillance, Epidemiology, and End Results Database

    Kwok Keung Yim, Yishou Deng

    Issue: Volume 11, Issue 2, June 2023
    Pages: 49-58
    Received: Apr. 19, 2023
    Accepted: May 15, 2023
    Published: May 24, 2023
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    Abstract: In general, we use the classical Cox proportional hazards model to derive factors that affect the prediction of patients diagnosed with thymic carcinoma (TC); however, when competing risks exist, the results can be biased. This study aimed to build a competing risk model for patients with TC to explore a more accurate method for assessing the relev... Show More
  • Knowledge, Sexual Behaviors on Human Papillomavirus Infections and Associated Factors: Survey Among Female Adolescents and Adults in the Republic of Congo

    Roch Bredin Bissala Nkounkou, Estelle Géraldine Essangui Same, Loic Pradel Kojom Foko, Parfait Christy Nganga, Paola Candyse Tsimba Lemba, Austin Mas Ngoulou Ntsiba, Luc Magloire Anicet Boumba, Fabien Roch Niama, Carole Else Eboumbou Moukoko

    Issue: Volume 11, Issue 2, June 2023
    Pages: 59-69
    Received: Apr. 26, 2023
    Accepted: May 17, 2023
    Published: May 29, 2023
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    Abstract: Background. Human papillomavirus (HPV) infection is sexually transmitted and responsible for anogenital warts and malignancies but its early diagnosis is hampered by the people’s lack of knowledge about the disease and prevention methods, especially in resource-limited countries. Objective. The study was designed to determine knowledge; attitudes a... Show More
  • Research Progress on the Mechanism and Treatment of Pyroptosis in Brain Glioma

    Xiaohui Han, Jie Zhou, Shihua Liu, Sen Yang, Aixia Sui

    Issue: Volume 11, Issue 2, June 2023
    Pages: 70-74
    Received: May 04, 2023
    Accepted: May 22, 2023
    Published: May 29, 2023
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    Abstract: Glioma is the most common fatal primary malignant brain tumor in the central nervous system (CNS). Currently, the main standard treatment is the combination of tumor resection, chemotherapy and radiotherapy. The World Health Organization (WHO) classifies glioma into four grades. Glioblastoma (GBM, WHO Grade 4) is the most aggressive type of glioma,... Show More
  • Epidermoid Carcinoma of the Breast: Report of an Observation and Review of the Literature

    Bangoura Mohamed Saliou, Diallo Mamadou Saliou, Soumah Mohamed Salifou, Youla Alpha Mohamed, Cisse Fode, Diallo Alseny, Camara Naby Laye Youssouf, Keita Abdoulaye, Yattara Abdoulaye, Soumaoro Labile Togba, Toure Aboubacar

    Issue: Volume 11, Issue 2, June 2023
    Pages: 75-77
    Received: Apr. 17, 2023
    Accepted: May 26, 2023
    Published: Jun. 09, 2023
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    Abstract: Introduction: primary squamous cell carcinoma is a well-known entity believed to be most common in the skin and other squamous cell-lined organs such as the esophagus and anus. Breast epidermoid carcinoma is very rare. Observation: we report the observation of a 30 years old woman, mother of 5 children and without particular pathological history ad... Show More
  • Effect of Angiotensin II on the Malignant Biological Behaviors of Colorectal Cancer Cells and Its Mechanism of Action

    Yingxue Yang, Xiaotian Yang, Qinghua Wang

    Issue: Volume 11, Issue 2, June 2023
    Pages: 78-85
    Received: May 17, 2023
    Accepted: Jun. 02, 2023
    Published: Jun. 09, 2023
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    Abstract: Objective To explore the effects of angiotensin II (AngII) and the angiotensin II type I receptor (AT1R) antagonist Losartan on the malignant biological behaviors of colorectal cancer (CRC) cells including proliferation, invasion, migration and epithelial-mesenchymal transition (EMT), as well as the underlying mechanism of action. Methods The CRC c... Show More